Article
When should thyroidectomy be performed in familial medullary thyroid carcinoma gene carriers with non-cysteine RET mutations?
Surgery - 1 Dec 2003
Niccoli-Sire Patricia, Murat Arnaud, Rohmer Vincent, Gibelin Hélène, Chabrier Gerard, Conte-Devolx Bernard, Visset Jacques, Ronceray Jean, Jaeck Daniel, Henry Jean François, Proye Charles, Carnaille Bruno, Kraimps Jean Louis
Abstract excerpt
BACKGROUND: Once familial medullary thyroid carcinoma gene carrier status is established, thyroidectomy must be performed in infancy for mutations in exon 10, but in familial medullary thyroid carcinoma with non-cysteine RET mutations, which is characterized by a late onset of C-cell disease, the appropriate timing of thyroidectomy is unclear. METHODS: We analyzed the cases of 76 patients who underwent...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.