Article
Genotype-phenotype based surgical concept of hereditary medullary thyroid carcinoma.
World journal of surgery - 1 May 2007
Machens Andreas, Dralle Henning
Abstract excerpt
BACKGROUND: Since DNA tests have enabled reliable identification of asymptomatic RET (rearranged during transfection) gene carriers, myriads of publications have appeared on genotype-phenotype relationships. A comprehensive appraisal of this body of evidence using evidence-based methodology is pending. METHODS: This study was based on systematic evaluation of the literature using evidence-based criteria. RESULTS:...
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