Article
Clueless, a conserved Drosophila gene required for mitochondrial subcellular localization, interacts genetically with parkin.
Disease models & mechanisms - 1 Jan 2000
Cox Rachel T, Spradling Allan C
Abstract excerpt
Parkinson's disease has been linked to altered mitochondrial function. Mutations in parkin (park), the Drosophila ortholog of a human gene that is responsible for many familial cases of Parkinson's disease, shorten life span, abolish fertility and disrupt mitochondrial structure. However, the rol...
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