Article
Association of a functional polymorphism in the adrenomedullin gene (ADM) with response to paroxetine.
The pharmacogenomics journal - 1 Apr 2010
Glubb D M, McHugh P C, Deng X, Joyce P R, Kennedy M A
Abstract excerpt
To identify genes that may be relevant to the molecular action of antidepressants, we investigated transcriptional changes induced by the selective serotonin reuptake inhibitor paroxetine in a serotonergic cell line. We examined gene expression changes after acute treatment with paroxetine and sought to validate microarray results by quantitative PCR (qPCR). Concordant transcriptional changes were confirmed for...
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