Article
Apolipoprotein A5 and lipoprotein lipase interact to modulate anthropometric measures in Hispanics of Caribbean origin.
Obesity (Silver Spring, Md.) - 1 Feb 2010
Smith Caren E, Tucker Katherine L, Lai Chao-Qiang, Parnell Laurence D, Lee Yu-Chi, Ordovás José M
Abstract excerpt
Apolipoprotein A5 (APOA5) and lipoprotein lipase (LPL) proteins interact functionally to regulate lipid metabolism, and single-nucleotide polymorphisms (SNPs) for each gene have also been associated independently with obesity risk. Evaluating gene combinations may be more effective than single SNP analyses in identifying genetic risk, but insufficient minor allele frequency (MAF) often limits evaluations of...
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