Article
APOA5 gene variation interacts with dietary fat intake to modulate obesity and circulating triglycerides in a Mediterranean population.
The Journal of nutrition - 1 Mar 2011
Sánchez-Moreno Carmen, Ordovás Jose M, Smith Caren E, Baraza Juan C, Lee Yu-Chi, Garaulet Marta
Abstract excerpt
APOA5 is one of the strongest regulators of plasma TG concentrations; nevertheless, its mechanisms of action are poorly characterized. Genetic variability at the APOA5 locus has also been associated with increased cardiovascular disease risk; however, this predisposition could be attenuated in the context of a prudent diet as traditionally consumed in the Mediterranean countries. We have investigated the...
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