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Article

Gastroesophageal reflux leads to esophageal cancer in a surgical model with mice.

BMC gastroenterology - 23 Jul 2009

Hao Jing, Liu Ba, Yang Chung S, Chen Xiaoxin

Abstract excerpt

BACKGROUND: Esophago-gastroduodenal anastomosis with rats mimics the development of human Barrett's esophagus and esophageal adenocarcinoma by introducing mixed reflux of gastric and duodenal contents into the esophagus. However, use of this rat model for mechanistic and chemopreventive studies i...

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Identifiers

PMID: 19627616
DOI: 10.1186/1471-230X-9-59
PMCID: PMC2723127

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19627616-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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