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Article

A serum free approach towards the conservation of chondrogenic phenotype during in vitro cell expansion.

Growth factors (Chur, Switzerland) - 1 Oct 2009

Ho Saey Tuan Barnabas, Yang Zheng, Hui Hoi Po James, Oh Kah Weng Steve, Choo Boon Hwa Andre, Lee Eng Hin

Abstract excerpt

OBJECTIVE: Functionally viable chondrocytes in sufficient quantity is crucial for the success of matrix associated autologous chondrocyte implantation. This is difficult with conventional methods as chondrocytes dedifferentiate during 2D expansion with the loss of their chondrogenic phenotype. Moreover, established protocols are dependent on the use of serum which is not without its drawbacks. This study sought...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19626506
DOI: 10.1080/08977190903137595

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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