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Article

Hypoxia Preconditioned Serum (HPS) Promotes Proliferation and Chondrogenic Phenotype of Chondrocytes In Vitro.

International journal of molecular sciences - 21 Jun 2023

Jiang Jun, Altammar Jannat, Cong Xiaobin, Ramsauer Lukas, Steinbacher Vincent, Dornseifer Ulf, Schilling Arndt F, Machens Hans-Günther, Moog Philipp

Abstract excerpt

Autologous chondrocyte implantation (ACI) for the treatment of articular cartilage defects remains challenging in terms of maintaining chondrogenic phenotype during in vitro chondrocyte expansion. Growth factor supplementation has been found supportive in improving ACI outcomes by promoting chondrocyte redifferentiation. Here, we analysed the chondrogenic growth factor concentrations in the human blood-derived...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37445617
DOI: 10.3390/ijms241310441
PMCID: PMC10341616

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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