Article
Thrombomodulin mutations in atypical hemolytic-uremic syndrome.
The New England journal of medicine - 23 Jul 2009
Delvaeye Mieke, Noris Marina, De Vriese Astrid, Esmon Charles T, Esmon Naomi L, Ferrell Gary, Del-Favero Jurgen, Plaisance Stephane, Claes Bart, Lambrechts Diether, Zoja Carla, Remuzzi Giuseppe, Conway Edward M
Abstract excerpt
BACKGROUND: The hemolytic-uremic syndrome consists of the triad of microangiopathic hemolytic anemia, thrombocytopenia, and renal failure. The common form of the syndrome is triggered by infection with Shiga toxin-producing bacteria and has a favorable outcome. The less common form of the syndrome, called atypical hemolytic-uremic syndrome, accounts for about 10% of cases, and patients with this form of the...
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