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Article

The functional promoter polymorphism of the coagulation factor XII gene is not associated with peripheral arterial disease.

Angiology - 1 Feb 2010

Yazdani-Biuki Babak, Krippl Peter, Brickmann Kerstin, Fuerst Florentine, Langsenlehner Uwe, Paulweber Bernhard, Pilger Ernst, Wascher Thomas C, Brezinschek Hans-Peter, Renner Wilfried

Abstract excerpt

Coagulation factor XII (FXII) plays a key role in both coagulation and fibrinolysis and has been associated with cardiovascular disease in some studies. Plasma FXIIa levels are strongly determined by a common functional polymorphism in the promoter of the FXII gene (F12-4C>T). To investigate the potential association of this polymorphism with peripheral arterial disease (PAD), we performed a case-control study...

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PMID: 19625260
DOI: 10.1177/0003319709337305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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