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Article

Influence of the F12 -4 C>T polymorphism on hemostatic tests.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Oct 2010

Corral Javier, Antón Ana I, Quiroga Teresa, González-Conejero Rocio, Pereira Jaime, Roldán Vanessa, Vicente Vicente, Mezzano Diego

Abstract excerpt

The common F12 -4 C>T polymorphism significantly regulates plasma levels of FXII, the first element of the intrinsic pathway of coagulation. Due to the robust effects that this pathway has on blood coagulation in vitro, the objective of our study was to evaluate the influence of this polymorphism on different hemostatic tests. We studied 46 hemostatic parameters in 566 participants: 280 patients with...

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PMID: 20814302
DOI: 10.1097/MBC.0b013e32833a9048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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