Article
Is the factor XIII 34Val/Leu polymorphism a protective factor for cerebrovascular disease?
British journal of haematology - 1 Jan 2003
Endler Georg, Funk Marion, Haering Daniela, Lalouschek Wolfgang, Lang Wilfried, Mirafzal Merdad, Wagner Oswald, Mannhalter Christine
Abstract excerpt
A frequent polymorphism in the factor XIII (FXIII) A-subunit gene, leading to a Val to Leu amino acid exchange at position 34, suggested to affect clot stability, has been associated with a decreased risk for venous thromboembolism and myocardial infarction. Its role in the development of stroke is still under investigation. Ninety-four patients with primary arterial intracerebral haemorrhage (mean age +/-...
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