Article
The V34L polymorphism of factor XIII and peripheral arterial disease.
International angiology : a journal of the International Union of Angiology - 1 Mar 2002
Renner W, Brodmann M, Pabst E, Stanger O, Wascher T C, Pilger E
Abstract excerpt
BACKGROUND: Factor XIII catalyzes crosslinking of fibrin in the last steps of the coagulation process. A common polymorphism in the gene for factor XIII A subunit (F13A1 V34L) has been associated with a decreased risk for coronary artery disease, cerebrovascular disease, and deep venous thrombosis. METHODS: To analyze the role of this polymorphism in peripheral arterial disease (PAD) we performed a case-control...
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