Article
Factor XIIIA Val34Leu polymorphism does not predict risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) Study.
Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2002
Aleksic Nena, Ahn Chul, Wang Yao-Wei, Juneja Harinder, Folsom Aaron R, Boerwinkle Eric, Wu Kenneth K
Abstract excerpt
Factor XIII catalyzes the cross-linking of fibrin. Cross-sectional studies have suggested that a common polymorphism site at residue 34 of the A subunit of factor XIII (FXIIIA) with a substitution of Leu for Val (FXIIIA Val34Leu) was associated with reduced coronary heart disease (CHD). This association has not been examined in prospective studies. Healthy subjects (n=15 792) were recruited from 4 US communities...
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