Article
[Construction of BP26 tagged vaccine strain and development of discriminating PCR for Brucella].
Wei sheng wu xue bao = Acta microbiologica Sinica - 1 Mar 2009
Wang Zhoujia, Zhen Qing, Qiao Feng, Wang Yufei, Du Xinying, Zhong Zhijun, Zhao Jin, Yu Yaqin, Huang Liuyu, Sun Yansong, Chen Zeliang
Abstract excerpt
OBJECTIVE: The wide application of live attenuated vaccine strains is limited because of drawbacks of residual virulence, similar antigenenicity to virulent strain and the difficulty to differentiate vaccination and natural infection. In this study, we modified the vaccine strain to prevent the d...
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