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A combined subunit vaccine comprising BP26, Omp25 and L7/L12 against brucellosis

1 Nov 2019

Abstract excerpt

The current vaccines against brucellosis, namely Brucella abortus strains 19 and RB51, prevent infection in animals but pose potential risks like virulence and attenuation reversal. In this milieu, although subunit vaccination using a single potent immunogen of B. abortus, e.g. BP26 or Omp25 or L7/L12 etc., appears as a safer alternative, nonetheless it confers inadequate protection against the zoonosis compared...

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PMID: 31971564
DOI: 10.1093/femspd/ftaa002

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