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Characteristics of Brucella abortus vaccine strain A19 reveals its potential mechanism of attenuated virulence.

Veterinary microbiology - 1 Mar 2021

Cheng Zhimin, Li Zichen, Yin Yi, Lian Zhengmin, Abdelgawad Hosny Ahmed, Hu Hai, Guan Xiang, Zuo Dong, Cai Yumei, Ding Chan, Wang Shaohui, Li Tao, Qi Jingjing, Tian Mingxing, Yu Shengqing

Abstract excerpt

Brucella vaccination is one of the most important strategies for controlling brucellosis in livestock. The A19 strain was the effective vaccine used to control brucellosis in China. However, the characteristics of physiological and attenuated virulence of the A19 strain are not investigated in detail. In this study, we compared the phenotypic characteristics of the A19 to the wild-type strain S2308. Virulence...

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PMID: 33582483
DOI: 10.1016/j.vetmic.2021.109007

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