Article
Matrix metalloproteinase 1 promoter polymorphisms and risk of myocardial infarction: a case-control study in a Spanish population.
Coronary artery disease - 1 Sept 2009
Román-García Pablo, Coto Eliecer, Reguero Julián R, Cannata-Andía Jorge B, Lozano Iñigo, Avanzas Pablo, Morís César, Rodríguez Isabel
Abstract excerpt
OBJECTIVES: Inherited and acquired risk factors contribute to the development of the atherosclerotic lesion and its most common clinical manifestation, myocardial infarction (MI). Multiple studies have suggested a role for matrix metalloproteinases (MMPs) in atherosclerosis, and several functional polymorphisms in the MMP-1 gene have been linked to the risk of MI. The aim of this study was to evaluate the...
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