Article
rs3918242 MMP9 gene polymorphism is associated with myocardial infarction in Mexican patients.
Genetics and molecular research : GMR - 4 Mar 2016
Rodríguez-Pérez J M, Vargas-Alarcón G, Posadas-Sánchez R, Zagal-Jiménez T X, Ortíz-Alarcón R, Valente-Acosta B, Tovilla-Zárate C, Nostroza-Hernández C, Pérez-Méndez O, Pérez-Hernández N
Abstract excerpt
Several studies have demonstrated that matrix metalloproteinases (MMPs) play a major role in atherosclerotic plaque disruption and lead to myocardial infarction (MI). We investigated the association between the MMP1 -1607 1G/2G (rs1799750), MMP3 -1612 5A/6A (rs3025058), and MMP9 -1562 C/T (rs3918242) polymorphisms and the risk of developing MI in a Mexican mestizo cohort. The genotype analysis was performed using...
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