Article
Analysis of MMP-7 and TIMP-2 gene polymorphisms in coronary artery disease and myocardial infarction: A Turkish case-control study.
The Kaohsiung journal of medical sciences - 1 Feb 2017
Alp Ebru, Yilmaz Akin, Tulmac Murat, Ugras Dikmen Asiye, Cengel Atiye, Yalcin Ridvan, Menevse Emine Sevda
Abstract excerpt
Matrix metalloproteinase (MMP) and tissue inhibitors of metalloproteinase (TIMP) have a significant role in tissue remodeling related to cardiac function. In earlier studies, MMP-7 A-181G (rs11568818), C-153T (rs11568819), C-115T (rs17886546), and TIMP-2 G-418C (rs8179090) polymorphisms have been studied in various diseases. However, association between coronary artery disease (CAD) and these polymorphisms has...
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