Article
Distinctive responses to nitrogen starvation in the dominant active mutants of the fission yeast Rheb GTPase.
Genetics - 1 Oct 2009
Murai Tomoka, Nakase Yukiko, Fukuda Keiko, Chikashige Yuji, Tsutsumi Chihiro, Hiraoka Yasushi, Matsumoto Tomohiro
Abstract excerpt
Rheb, a Ras-like small GTPase conserved from human to yeast, controls Tor kinase and plays a central role in the regulation of cell growth depending on extracellular conditions. Rhb1 (a fission yeast homolog of Rheb) regulates amino acid uptake as well as response to nitrogen starvation. In this...
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