Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tsc1+ and tsc2+ regulate arginine uptake and metabolism in Schizosaccharomyces pombe.

The Journal of biological chemistry - 26 Mar 2004

van Slegtenhorst Marjon, Carr Erikka, Stoyanova Radka, Kruger Warren D, Henske Elizabeth Petri

Abstract excerpt

Mutations in either TSC1 or TSC2 cause tuberous sclerosis complex, an autosomal dominant disorder characterized by seizures, mental retardation, and benign tumors of the skin, brain, heart, and kidneys. Homologs for the TSC1 and TSC2 genes have been identified in mouse, rat, Fugu, Drosophila, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Schizosaccharomyces pombe Proteins
Share to Amino Acid Transport Systems
Share to Arginine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blotting, Northern

Share to GTP Phosphohydrolases

Share to Monomeric GTP-Binding Proteins

Share to Neuropeptides

Share to Schizosaccharomyces

Source

Identifiers

PMID: 14718525
DOI: 10.1074/jbc.M313874200

Genes

TSC1
TSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14718525-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tsc1+ and tsc2+ regulate arginine uptake and metabolism in Schizosaccharomyces pombe.PMID 14718525Read ↗

Pas1, a G1 cyclin, regulates amino acid uptake and rescues a delay in G1 arrest in Tsc1 and Tsc2 mutants in Schizosaccharomyces pombe.Semantic proximity Read ↗

A defect in protein farnesylation suppresses a loss of Schizosaccharomyces pombe tsc2+, a homolog of the human gene predisposing to tuberous sclerosis complex.Semantic proximity Read ↗

The Birt-Hogg-Dube and tuberous sclerosis complex homologs have opposing roles in amino acid homeostasis in Schizosaccharomyces pombe.Semantic proximity Read ↗

Opposite Effects of Tor1 and Tor2 on Nitrogen Starvation Responses in Fission YeastSemantic proximity Read ↗

Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling.Semantic proximity Read ↗

The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction.Semantic proximity Read ↗

TORC1 signaling is governed by two negative regulators in fission yeast.Semantic proximity Read ↗

Regulation of leucine uptake by tor1+ in Schizosaccharomyces pombe is sensitive to rapamycin.Semantic proximity Read ↗

Genetics and Molecular Biology of Tuberous Sclerosis ComplexSemantic proximity Read ↗

Drosophila TCTP is essential for growth and proliferation through regulation of dRheb GTPase.Semantic proximity Read ↗

The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses.Semantic proximity Read ↗

Tuberous sclerosis complex: linking growth and energy signaling pathways with human disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.