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Do folate, vitamins B₆ and B₁₂ play a role in the pathogenesis of migraine? The role of pharmacoepigenomics.

CNS & neurological disorders drug targets - 1 Jan 2014

Shaik Munvar Miya, Tan Huay Lin, Kamal Mohammad A, Gan Siew Hua

Abstract excerpt

Migraine is a neurovascular disease that has classically been attributed to multifactorial aetiologies, with genetic components and environmental interactions considered the main influence. Genes such as flavoenzyme 5, 10- methylenetetrahydrofolate reductase (MTHFR), especially the C677T variant, have been associated with elevated plasma homocysteine levels. This elevation in homocysteine results in an array of...

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PMID: 24040787
DOI: 10.2174/18715273113129990112

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MTHFR

Variants

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Do folate, vitamins B₆ and B₁₂ play a role in the pathogenesis of migraine? The role of pharmacoepigenomics.PMID 24040787Read ↗

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