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Article

Functional variant (-1304T>G) in the MKK4 promoter is associated with decreased risk of acute myeloid leukemia in a southern Chinese population.

Cancer science - 1 Aug 2011

Jiang Lan, Zhou Ping, Sun Aining, Zheng Jian, Liu Bin, You Yonghe, Zhang Chun, Wu Depei, Zhou Yifeng

Abstract excerpt

As a member of the MAPK kinase family, mitogen-activated protein kinase kinase (MKK) 4 (NM_003010.2) is know to be involved in the regulation of apoptosis, inflammation, and tumorigenesis. Several polymorphisms have been identified in the promoter region of the MKK4 gene and we hypothesized that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21518142
DOI: 10.1111/j.1349-7006.2011.01965.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21518142-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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