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Article

Associations between polymorphisms in the SYK promoter and susceptibility to sporadic colorectal cancer in a Southern Han Chinese population - a short report.

Cellular oncology (Dordrecht, Netherlands) - 1 Apr 2015

Peng Hui, Huang Jun, Hu Ying, Wei Yisheng, Liu Huanliang, Huang Meijin, Wang Lei, Wang Jianping

Abstract excerpt

PURPOSE: Down-regulated expression of the putative tumor suppressor gene spleen tyrosine kinase (SYK) is strongly associated with the development of various cancers, including colorectal cancer (CRC). SYK gene promoter polymorphisms have been shown to be involved in the pathogenesis of multiple malignant tumors. In this study, we investigated associations of SYK gene promoter polymorphisms with the susceptibility...

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Source

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Identifiers

PMID: 25921550
DOI: 10.1007/s13402-014-0208-2
PMCID: PMC13004175

Genes

SYK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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