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Article

The role of p53 as a surrogate marker for chemotherapeutical responsiveness in ovarian cancer.

Journal of cancer research and clinical oncology - 1 Jan 2010

Bauerschlag Dirk O, Schem Christian, Weigel Marion T, Von Kaisenberg Constantin, Strauss Alexander, Bauknecht Thomas, Maass Nicolai, Meinhold-Heerlein Ivo

Abstract excerpt

INTRODUCTION: In advanced ovarian cancers (OCs), p53 mutations are frequently observed. The objective of this study was to explore the value of the p53 mutational status, using four different techniques, in advanced OC patients as a predictive marker for responsiveness to platinum-based chemotherapy. METHODS: One hundred and four, mostly serous papillary OC specimens were analyzed, of which all received a...

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Share to Antineoplastic Combined Chemotherapy Protocols
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Immunohistochemistry

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Share to Polymorphism, Single-Stranded Conformational

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Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 19609560
DOI: 10.1007/s00432-009-0639-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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