Article
p53 mutations in epithelial ovarian cancers: possible role in predicting chemoresistance.
Cancer journal (Sudbury, Mass.) - 1 Jan 2000
Laframboise S, Chapman W, McLaughlin J, Andrulis I L
Abstract excerpt
PURPOSE: The investigators undertook a retrospective study to determine (1) whether p53 mutations are predictors of survival in patients with advanced epithelial ovarian cancer, (2) whether p53 status by sequencing is associated with established prognostic indicators, and (3) the agreement of results between direct sequencing of p53 mutations and immunohistochemistry. MATERIAL AND METHODS: This study was...
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