Article
Inflammatory state and stress condition in weight-lowering Lys109Arg LEPR gene polymorphism carriers.
Archives of medical research - 1 May 2009
Abete Iztiar, Goyenechea Estíbaliz, Crujeiras Ana Belen, Martínez J Alfredo
Abstract excerpt
BACKGROUND AND AIMS: Carrying variants on the leptin receptor gene (LEPR) may have an impact on inflammatory and stress markers. Thus, the aim of the study was to analyze the role of the Lys109Arg LEPR gene polymorphism on inflammatory (leptin and IL-6) and stress (cortisol) markers in obese subjects who followed a hypocaloric diet designed to lose weight. METHODS: One hundred and seventy (80 females/90 males)...
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