Article
LEPR polymorphism may affect energy balance during weight loss among Brazilians obese adolescents.
Neuropeptides - 1 Dec 2017
Corgosinho Flávia Campos, Almeida Sandro Soares, Tock Lian, Pesquero João Bosco, Araújo Ronaldo Carvalho, Clemente Ana Paula Grotti, Dal'Molin Netto Bárbara, da Silveira Campos Raquel Munhoz, Masquio Deborah Cristina Landi, de Carvalho Ferreira Joana Pereira, de Lima Sanches Priscila, de Piano Ganen Aline, Rogero Marcelo Macedo, Oyama Lila Missae, Tufik Sergio, de Mello Marco Túlio, Dâmaso Ana Raimunda
Abstract excerpt
OBJECTIVE: Leptin is an adipokine released mainly by adipose tissue, with many functions including regulation of energy balance. However, little is known about the effect of LEPR polymorphism on orexigenic and anorexigenic neuropeptides. Thus, the aim of the present study is to verify the influence of LEPR polymorphism (rs2767485) on serum orexigenic (NPY, MCH and AgRP) and anorexigenic (Leptin and α-MSH)...
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