Article
A non-death role of the yeast metacaspase: Yca1p alters cell cycle dynamics.
PloS one - 13 Aug 2008
Lee Robin E C, Puente Lawrence G, Kaern Mads, Megeney Lynn A
Abstract excerpt
Caspase proteases are a conserved protein family predominantly known for engaging and executing apoptotic cell death. Nevertheless, in higher eukaryotes, caspases also influence a variety of cell behaviors including differentiation, proliferation and growth control. S. cerevisiae expresses a primordial caspase, yca1, and exhibits apoptosis-like death under certain stresses; however, the benefit of a dedicated...
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