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Article

Clinical effects of high oral dose of donepezil for patients with Alzheimer's disease in Japan.

Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society - 1 Jun 2009

Nozawa Motohiro, Ichimiya Yosuke, Nozawa Eiko, Utumi Yushi, Sugiyama Hideki, Murayama Norio, Iseki Eizo, Arai Heii

Abstract excerpt

BACKGROUND: Donepezil 10 mg/day gained approval in Japan in August 2007 for the treatment of cognitive dysfunction in advanced Alzheimer's disease. METHODS: We evaluated the efficacy and adverse effects of donepezil when the dose was increased to 10 mg/day in 61 Japanese patients with Alzheimer's disease. Cognitive function was evaluated using the Revised Hasegawa Dementia Scale and mini-mental state examination...

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Identifiers

PMID: 19604325
DOI: 10.1111/j.1479-8301.2009.00291.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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