Article
The roles of apolipoprotein E3 and CYP2D6 (rs1065852) gene polymorphisms in the predictability of responses to individualized therapy with donepezil in Han Chinese patients with Alzheimer's disease.
Neuroscience letters - 12 Feb 2016
Lu Jin, Fu Jianliang, Zhong Yuan, Chen Pengguo, Yang Quanjun, Zhao Yuwu, Wan Lili, Guo Cheng
Abstract excerpt
AIM: Polymorphisms in the apolipoprotein E and CYP2D6 genes are widely reported to be related to Alzheimer's disease. However, few studies have focused on the relationship between polymorphisms in apolipoprotein E and CYP2D6 (rs1065852) genes and therapeutic responses to donepezil (DNP). This study explored the influence of apolipoprotein E3 and CYP2D6 (rs1065852) gene polymorphisms on therapeutic responses to...
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