Article
Relation between CYP2D6 genotype, personality, neurocognition and overall psychopathology in healthy volunteers.
Pharmacogenomics - 1 Jul 2009
Peñas-LLedó Eva M, Dorado Pedro, Pacheco Rodrigo, González Idilio, LLerena Adrián
Abstract excerpt
AIMS: A lower serotonin/higher dopamine tone in CYP2D6 poor metabolizers (PMs) versus extensive metabolizers (EMs) has been postulated, which is consistent with our prior research showing behavioral traits related to anxiety and impulsivity in PMs. This tone could also be related to PMs vulnerability to cognitive functioning and/or psychopathology. Therefore, the present study aimed to analyze the relationship...
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