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Article

CYP2D6 polymorphism in patients with eating disorders.

The pharmacogenomics journal - 1 Apr 2012

Peñas-Lledó E M, Dorado P, Agüera Z, Gratacós M, Estivill X, Fernández-Aranda F, Llerena A

Abstract excerpt

CYP2D6 polymorphism is associated with variability in drug response, endogenous metabolism (that is, serotonin), personality, neurocognition and psychopathology. The relationship between CYP2D6 genetic polymorphism and the risk of eating disorders (ED) was analyzed in 267 patients with ED and in 285 controls. A difference in the CYP2D6 active allele distribution was found between these groups. Women carrying more...

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PMID: 20877302
DOI: 10.1038/tpj.2010.78

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