Article
Association between low-activity allele of cathecolamine-O-methyl-transferase (COMT) and Borderline Personality Disorder in an Italian population.
Behavioral medicine (Washington, D.C.) - 1 Jan 2013
Lazzaretti Matteo, Fabbro Dora, Sala Michela, Del Toso Kether, de Vidovich Giulia, Marraffini Elisa, Morandotti Niccolò, Gambini Francesca, Barale Francesco, Balestrieri Matteo, Damante Giuseppe, Caverzasi Edgardo, Brambilla Paolo
Abstract excerpt
The objective of the present study was to test the association between Borderline Personality Disorder (BPD) and the cathecolamine-O-methyl-transferase (COMT) low-activity (Met158) single nucleotide polymorphism (SNP). In this case-control study, DNA was obtained from venous blood of 19 BPD patients and 36 healthy subjects. COMT-Val158Met single-nucleotide polymorphism was genotyped by predesigned SNP assay. The...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.