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Article

A network model of a cooperative genetic landscape in brain tumors.

JAMA - 15 Jul 2009

Bredel Markus, Scholtens Denise M, Harsh Griffith R, Bredel Claudia, Chandler James P, Renfrow Jaclyn J, Yadav Ajay K, Vogel Hannes, Scheck Adrienne C, Tibshirani Robert, Sikic Branimir I

Abstract excerpt

CONTEXT: Gliomas, particularly glioblastomas, are among the deadliest of human tumors. Gliomas emerge through the accumulation of recurrent chromosomal alterations, some of which target yet-to-be-discovered cancer genes. A persistent question concerns the biological basis for the coselection of these alterations during gliomagenesis. OBJECTIVES: To describe a network model of a cooperative genetic landscape in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19602686
DOI: 10.1001/jama.2009.997
PMCID: PMC4447713

Genes

ANXA7
CYCS
MYC
PDCD4
POLD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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