Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of matrix metalloproteinase-1 promoter genotype on interleukin-1beta-induced matrix metalloproteinase-1 production in human periodontal ligament cells.

Journal of periodontal research - 1 Feb 2010

Cao Z, Li C, Xiang J

Abstract excerpt

BACKGROUND AND OBJECTIVE: Our previous studies have shown that a single nucleotide polymorphism at nucleotide -1607 of the human matrix metalloproteinase-1 (MMP-1) promoter is associated with the severity of periodontal disease. The purpose of this study was to evaluate the effect of different MMP-1 promoter genotypes on interleukin-1beta-induced MMP-1 production in human periodontal ligament cells. MATERIAL AND...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinogens
Share to Guanine
Share to Homozygote

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interleukin-1beta

Share to Matrix Metalloproteinase 1

Share to Periodontal Ligament

Share to Polymorphism, Restriction Fragment Length

Share to Tetradecanoylphorbol Acetate

Source

Identifiers

PMID: 19602108
DOI: 10.1111/j.1600-0765.2009.01208.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of matrix metalloproteinase-1 promoter genotype on interleukin-1beta-induced matrix metalloproteinase-1 production in human periodontal ligament cells.PMID 19602108Read ↗

The effect of a single nucleotide polymorphism in the matrix metalloproteinase-1 (MMP-1) promoter on force-induced MMP-1 expression in human periodontal ligament cells.Semantic proximity Read ↗

Effect of MMP-1 promoter polymorphisms on GCF MMP-1 levels and outcome of periodontal therapy in patients with severe chronic periodontitis.Semantic proximity Read ↗

Investigation of matrix metalloproteinase-1--1607 1G/2G polymorphism in a Turkish population with periodontitis.Semantic proximity Read ↗

Strong and persistent microbial and inflammatory stimuli overcome the genetic predisposition to higher matrix metalloproteinase-1 (MMP-1) expression: a mechanistic explanation for the lack of association of MMP1-1607 single-nucleotide polymorphism genotypes with MMP-1 expression in chronic periodontitis lesions.Semantic proximity Read ↗

MMP1-1607 polymorphism increases the risk for periapical lesion development through the upregulation MMP-1 expression in association with pro-inflammatory milieu elements.Semantic proximity Read ↗

MMP-1 promoter polymorphism: association with chronic periodontitis severity in a Brazilian population.Semantic proximity Read ↗

MMP-1 promoter gene polymorphism and susceptibility to chronic periodontitis in a Chinese population.Semantic proximity Read ↗

Genetic variations in the matrix metalloproteinase-1 promoter and risk of susceptibility and/or severity of chronic periodontitis in the Czech population.Semantic proximity Read ↗

Matrix metalloproteinase-1 and -3 gene promoter polymorphisms in Japanese patients with periodontitis.Semantic proximity Read ↗

Genetic polymorphisms in the MMP-1 and MMP-3 gene may contribute to chronic periodontitis in a Brazilian population.Semantic proximity Read ↗

Polymorphisms in the IL-1A gene are correlated with levels of interleukin-1alpha protein in gingival crevicular fluid of teeth with severe periodontal disease.Semantic proximity Read ↗

Effect of the interleukin-1 genotype on outcomes of regenerative periodontal therapy with bone replacement grafts.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.