Article
Genetic variations in the matrix metalloproteinase-1 promoter and risk of susceptibility and/or severity of chronic periodontitis in the Czech population.
Journal of clinical periodontology - 1 Aug 2004
Hollá L Izakovicová, Jurajda M, Fassmann A, Dvorakova N, Znojil V, Vacha J
Abstract excerpt
OBJECTIVES: Matrix metalloproteinase-1 (MMP-1) is a potent enzyme degrading extracellular matrix that was implicated in the pathogenesis of chronic periodontitis. Therefore, the aim of our study was to examine the association between three promoter polymorphisms of the MMP-1 gene and chronic periodontitis susceptibility and/or severity in a Czech population. MATERIALS AND METHODS: A total of 329 Caucasian...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
