Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Filaggrin null mutations in childhood atopic dermatitis among the Chinese.

International journal of immunogenetics - 1 Aug 2009

Ching G K, Hon K-L, Ng P-C, Leung T-F

Abstract excerpt

Atopic dermatitis (AD) is associated with loss or reduced expression of filaggrin (FLG). We evaluated five FLG null mutations, namely R501X, 2282del4, R2447X, S2554X, and S2889X, in 174 Chinese children with AD and 191 matched controls. 2282del4, R2447X, S2554X and S2889X mutations were not found...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Child
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dermatitis, Atopic

Share to Filaggrin Proteins

Share to Heterozygote

Share to Intermediate Filament Proteins

Source

Identifiers

PMID: 19602001
DOI: 10.1111/j.1744-313X.2009.00859.x

Genes

FLG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19602001-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Filaggrin null mutations in childhood atopic dermatitis among the Chinese.PMID 19602001Read ↗

Mutations analysis in filaggrin gene in northern China patients with atopic dermatitis.Semantic proximity Read ↗

Novel FLG null mutations in Korean patients with atopic dermatitis and comparison of the mutational spectra in Asian populationsSemantic proximity Read ↗

Mutations in the filaggrin gene in Han Chinese patients with atopic dermatitis.Semantic proximity Read ↗

Wide spectrum of filaggrin-null mutations in atopic dermatitis highlights differences between Singaporean Chinese and European populations.Semantic proximity Read ↗

Prevalence of FLG loss‐of‐function mutations R501X, 2282del4, and R2447X in Spanish children with atopic dermatitisSemantic proximity Read ↗

Filaggrin gene polymorphisms in Indian children with atopic dermatitis: A cross-sectional multicentre study.Semantic proximity Read ↗

Filaggrin Mutation in Korean Patients with Atopic Dermatitis.Semantic proximity Read ↗

Filaggrin null mutations are associated with atopic dermatitis and elevated levels of IgE in the Japanese population: a family and case-control study.Semantic proximity Read ↗

Null mutations in the filaggrin gene (FLG) determine major susceptibility to early-onset atopic dermatitis that persists into adulthood.Semantic proximity Read ↗

Filaggrin gene mutations are associated with independent atopic asthma in Chinese patients.Semantic proximity Read ↗

Filaggrin loss-of-function mutations are not associated with atopic dermatitis that develops in late childhood or adulthood.Semantic proximity Read ↗

Analysis of four prevalent filaggrin mutations (R501X, 2282del4, R2447X and S3247X) in Austrian and German patients with atopic dermatitis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.