Article
Advances in the genetics of glioblastoma: are we reaching critical mass?
Nature reviews. Neurology - 1 Aug 2009
Purow Benjamin, Schiff David
Abstract excerpt
Glioblastoma is the most common and highest-grade brain tumor, causing over 10,000 deaths each year in the US alone. Given the resistance of this tumor to standard surgery, radiation and chemotherapy, an understanding of the underlying genetic lesions is vital. Recent efforts to comprehensively profile glioblastomas using the latest technologies, both by The Cancer Genome Atlas (TCGA) project and by other groups,...
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