Article
Sequencing the next generation of glioblastomas.
Critical reviews in clinical laboratory sciences - 1 Jun 2018
Jovčevska Ivana
Abstract excerpt
The most aggressive brain malignancy, glioblastoma, accounts for 60-70% of all gliomas and is uniformly fatal. According to the molecular signature, glioblastoma is divided into four subtypes (proneural, neural, classical, and mesenchymal), each with its own genetic background. The Cancer Genome Atlas project provides information about the most common genetic changes in glioblastoma. They involve mutations in...
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