<i>Mycobacterium abscessus</i> Glycopeptidolipids Mask Underlying Cell Wall Phosphatidyl-<i>myo</i>-Inositol Mannosides Blocking Induction of Human Macrophage TNF-α by Preventing Interaction with TLR2

Abstract excerpt

Mycobacterium abscessus causes disease in patients with structural abnormalities of the lung, and it is an emerging pathogen in patients with cystic fibrosis. Colonization of the airways by nontuberculous mycobacteria is a harbinger of invasive lung disease. Colonization is facilitated by biofilm formation, with M. abscessus glycopeptidolipids playing an important role. M. abscessus can transition between a...

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