Article
Overexpression of proinflammatory TLR-2-signalling lipoproteins in hypervirulent mycobacterial variants.
Cellular microbiology - 1 May 2011
Roux Anne-Laure, Ray Aurélie, Pawlik Alexandre, Medjahed Halima, Etienne Gilles, Rottman Martin, Catherinot Emilie, Coppée Jean-Yves, Chaoui Karima, Monsarrat Bernard, Toubert Antoine, Daffé Mamadou, Puzo Germain, Gaillard Jean-Louis, Brosch Roland, Dulphy Nicolas, Nigou Jérôme, Herrmann Jean-Louis
Abstract excerpt
Changes in the cell envelope composition of mycobacteria cause major changes in cytokine profiles of infected antigen presenting cells. We describe here the modulation of inflammatory responses by Mycobacterium abscessus, an emerging pathogen in cystic fibrosis. M. abscessus is able to switch fro...
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