Article
Expression of xenobiotic and steroid hormone metabolizing enzymes in hepatocellular tumors of the non-cirrhotic liver.
Pathology, research and practice - 1 Jan 2009
Haas Susanne, Merkelbach-Bruse Sabine, Justenhoven Christina, Brauch Hiltrud, Fischer Hans-Peter
Abstract excerpt
Hepatocellular adenomas (HCA) and some hepatocellular carcinomas (HCC) arise in the non-cirrhotic liver. Although the liver is involved in the metabolism of a huge number of exogenous and endogenous substances, little is known about the role of metabolic enzymes in the development of liver tumors in the absence of cirrhosis. We analyzed the expression of glutathione S-transferases (GST) and cytochrome P450...
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