Article
Association between nonalcoholic hepatic steatosis and hepatic cytochrome P-450 3A activity.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Mar 2007
Kolwankar Dhanashri, Vuppalanchi Raj, Ethell Brian, Jones David R, Wrighton Steven A, Hall Stephen D, Chalasani Naga
Abstract excerpt
BACKGROUND & AIMS: Comorbidities associated with nonalcoholic fatty liver often require therapy with medications (eg, statins) metabolized by cytochrome P-450 3A (CYP3A). There is significant interindividual variability in CYP3A expression. However, human studies that systematically examined the...
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