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Article

Alcohol Metabolism in the Progression of Human Nonalcoholic Steatohepatitis.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Aug 2018

Li Hui, Toth Erica, Cherrington Nathan J

Abstract excerpt

Alcohol metabolism is a well-characterized biological process that is dominated by the alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) families. Nonalcoholic steatohepatitis (NASH) is the advanced inflammatory stage of nonalcoholic fatty liver disease (NAFLD) and is known to alter the metabolism and disposition of numerous drugs. The purpose of this study was to investigate the alterations in...

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Source

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Identifiers

PMID: 29718361
DOI: 10.1093/toxsci/kfy106
PMCID: PMC6659028

Genes

ADH1A
ADH1B
ADH4
ALDH1A1
ALDH1B1
ALDH2
ALDH4A1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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