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Article

Loss of heterozygosity of succinate dehydrogenase B mutation by direct sequencing in synchronous paragangliomas.

Cancer genetics and cytogenetics - 15 Jul 2009

Prasad Pinki, Kant Jeffrey A, Wills Marcia, O'Leary Mandy, Lovvorn Harold, Yang Elizabeth

Abstract excerpt

Extraadrenal pheochromocytomas and paragangliomas are rare entities within the pediatric population. We report the presentation of three synchronous extra-adrenal abdominal paragangliomas in an adolescent boy who carries a germline mutation in the succinate dehydrogenase B (SDHB) gene. Loss of heterozygosity of this allele was demonstrated by direct sequencing of DNA from two of his tumors, confirming loss of...

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Source

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Identifiers

PMID: 19596260
DOI: 10.1016/j.cancergencyto.2009.04.009
PMCID: PMC2927361

Genes

SDHB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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