Article
[The mutations of germline succinate dehydrogrnase subunit B (SDHB) in sporadic paragangliomas].
Shanghai kou qiang yi xue = Shanghai journal of stomatology - 1 Aug 2011
Zu Ting-jian, Jia Mu-yun, Yuan Rong-tao, Bu Ling-xue, Yao Ru-yong
Abstract excerpt
PURPOSE: The purpose of this study was to investigate the somatic mutations of human mitochondria succinate dehydrogenase subunit B (SDHB) in sporadic paragangliomas. METHODS: Eight exons of SDHB gene in 8 sporadic paragangliomas cases were amplified by PCR and sequenced, respectively. The sequences were analyzed to find mutations compared with human homology sequence in Genebank and SNP database. RESULTS: Nine...
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