Article
Phosphatidylinositol 4-kinase: gene structure and requirement for yeast cell viability.
Science (New York, N.Y.) - 26 Nov 1993
Flanagan C A, Schnieders E A, Emerick A W, Kunisawa R, Admon A, Thorner J
Abstract excerpt
Phosphatidylinositol (PtdIns) 4-kinase catalyzes the first step in the biosynthesis of PtdIns-4,5-bisphosphate (PtdIns[4,5]P2). Hydrolysis of PtdIns[4,5]P2 in response to extracellular stimuli is thought to initiate intracellular signaling cascades that modulate cell proliferation and differentia...
Topics
- 1-Phosphatidylinositol 4-Kinase
- Amino Acid Sequence
- Cloning, Molecular
- Gene Expression
- Genes, Fungal
- Molecular Sequence Data
- Molecular Weight
- Mutation
- Phosphatidylinositol 4,5-Diphosphate
- Phosphatidylinositol Phosphates
- Phosphotransferases (Alcohol Group Acceptor)
- Polymerase Chain Reaction
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins